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Abstract
1.
Member Organization : Oklahoma
Activation of PPARalpha has been demonstrated to inhibit tumor growth and angiogenesis, yet the mechanisms behind these actions remain to be characterized. The present study examined the effects of PPARalpha activation on the HIF-1alpha signaling...

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2.
Member Organization : Oklahoma
This project addresses the broad area of translational science to develop drugs for malaria. There are no effective vaccines for human malaria and the efficacy of the available drugs, which are not free of toxicity, is declining as resistance emerges....

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3.
Member Organization : Oklahoma
SHetA2 is the first compound of its kind to pass National Cancer Insititute pre-clinical testing and is available for FDA in-human trials for the prevention of ovarian cancer. However, SHetA2 may function poorly in human clinical trials and analogs...

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4.
Member Organization : Oklahoma
Young children with severe motor impairments are at great risk of secondary impairments in social, perceptual, and cognitive development. Power wheelchairs can be an effective early intervention tool that provides independent mobility. However,...

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5.
Member Organization : Oklahoma
Machine learning techniques have found widespread applications in bioinformatics. Such techniques meet the clinical requirements for various classification and prediction problems, which are difficult to model using traditional methods. For example,...

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